Synthesis and serological interactions of H. pylori urease fragment 321-339 n-terminally immobilized on the cellulose.

نویسندگان

  • Beata Kolesińska
  • Sebastian Grabowski
  • Wiesław Kaca
  • Zbigniew J Kamiński
چکیده

Antigenic epitopes F8 (SIKEDVQF) and UB-33 (UreB fragment with residues 321-339: CHHLDKSIKEDVQFADSRI) in H. pylori urease that induces neutralizing antibody production were prepared on the cellulose plate from N- to C-terminus using CDMT as a coupling reagent. Reaction of both epitopes with sera of patients with medically confirmed atherosclerosis was studied. Strong, selective reactions of both peptides with some patients sera were observed.

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عنوان ژورنال:
  • Acta poloniae pharmaceutica

دوره 63 4  شماره 

صفحات  -

تاریخ انتشار 2006